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CAR-T Therapy Revolutionizing Cancer Treatment

The Human Genome Project’s completion in 2003 paved the way for personalized medicines tailored to individual patients. 

One groundbreaking example is CAR-T therapy, an innovative immunotherapy that reprograms a patient’s own T-cells to target and destroy cancer cells.

In this process, researchers extract T-cells, modify them in a lab to produce chimeric antigen receptors (CARs) and then reintroduce these CARs into the patient to actively target and eradicate cancer. Researchers are currently developing nearly 800 CAR-T therapies, with a focus on enhancing efficacy, improving safety and streamlining manufacturing to further transform cancer care.

Two scientists in lab coats and gloves examine a vial together in a laboratory, standing next to a computer monitor and illuminated workspace with various lab equipment around them.

Our Work in Action

To maintain America’s global leadership, we need to support the next generation of innovation in medicine.

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Silver 3D letters on a brick wall spell “Research Triangle Park” next to a geometric logo featuring blue and red angled shapes forming a triangle.

North Carolina’s Research Triangle Park is a Powerhouse for Biopharma Innovation and Economic Growth

Decades of investment in North Carolina’s biopharmaceutical industry has spurred the state’s economy, workforce development and community engagement.

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A group of people stands in front of a modern office building at a construction site, posing behind a row of shovels and white hard hats on a mound of dirt, with Gilead logos visible on the signs in front.

Gilead Boosts U.S. Manufacturing Capacity to Advance Next-Generation Biologics

Gilead’s new Bay Area facility is supporting the American workforce while underscoring its commitment to strengthening U.S. biopharmaceutical leadership.

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A large modern industrial building with a white roof, red accents, and glass windows is surrounded by parked cars, trees, and landscaping. The setting appears to be a business or manufacturing facility.

Astellas Strengthens Manufacturing in America to Fuel Gene Therapy Innovation

Astellas opened a state-of-the-art gene therapy manufacturing facility in Sanford, North Carolina, advancing innovation for rare diseases with no or minimal treatment options and strengthening the world-leading U.S. biopharmaceutical manufacturing ecosystem.

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A modern building with "RayzeBio" signage, large windows, a blue accent, landscaped grounds, and an American flag flying on a flagpole in front.

Bristol Myers Squibb Expands U.S. Manufacturing Presence to Advance Cancer Innovation

Bristol Myers Squibb opened a first-of-its-kind radiopharmaceutical manufacturing facility in Indianapolis, Indiana, bringing significant investment and high-skilled job opportunities to the region.

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A large, modern white building with the Amgen logo on the exterior, surrounded by green grass and paved walkways, under a clear blue sky.

Amgen Drives U.S. Manufacturing Leadership

Amgen is at the forefront of innovation, developing medicines to solve some of the world’s toughest diseases and paving the way to bring next-generation therapies to patients.

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AstraZeneca Invests in the U.S. to Power the Future of Cell Therapy

AstraZeneca’s investment in Maryland creates high-quality jobs and advances next-generation cancer treatments.

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