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A mood disorder that causes severe symptoms such as persistent sad, anxious, or “empty” feelings, fatigue and decreased energy. It can interfere with a person’s ability to work, sleep, eat, concentrate, make decisions and enjoy life.



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A New Era for Mental Health

Learn about the 138 medicines in development to treat mental illnesses.

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Advancing Mental Health by Reducing Stigma and Improving Treatment

Recently, the Centers for Disease Control and Prevention announced suicide rates in the U.S. increased by 25 percent over the last two decades, and more than half of those who died by the disease had not been diagnosed with a mental health condition.

Researcher Profile: Wayne Drevets image

Researcher Profile: Wayne Drevets

Dr. Drevets is a scientist at Janssen Research & Development, LLC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, where he oversees the development of new treatments for mood disorders, such as major depressive disorder, treatment resistant depression and suicidality.

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Rethinking Psychiatric Treatment: Dr. Husseini Manji

Today, Dr. Husseini Manji is the global therapeutic head for neuroscience at Janssen. In this role, he has researched the ways in which psychiatric disorders alter a patient’s cellular systems, resulting in symptoms or negative behaviors.